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Lipoma endobronquial Endobronchial lipoma
R. Dacal,J. Abal,P.J. Marcos,M.C. Montero
Anales del Sistema Sanitario de Navarra , 2012,
Abstract: El lipoma endobronquial es un tumor benigno extremadamente raro, que suele causar síntomas por obstrucción bronquial. En la tomografía computarizada de tórax se presenta como una masa homogénea de densidad grasa que no capta contraste. El diagnóstico definitivo se realiza con broncoscopia y biopsia del tumor. El tratamiento de elección es la resección por vía endoscópica. Presentamos un caso de lipoma endobronquial en una paciente de 74 a os, con antecedente de carcinoma papilar de tiroides, resecado por vía endoscópica. Endobronchial lipoma is an extremely rare benign tumour, which usually causes symptoms related with bronchial obstruction. Chest computed tomography shows a homogeneous mass with fat density and without contrast enhancement. Definitive diagnosis is made with bronchoscopy and biopsy of the tumour. The treatment of choice is endoscopic resection. We present a case of an endobronchial lipoma in a 74 year-old patient, with a medical history of papilar thyroid gland carcinoma, resected endoscopically.
Mechanisms of Ectopic Gene Conversion
P.J. Hastings
Genes , 2010, DOI: 10.3390/genes1030427
Abstract: Gene conversion (conversion), the unidirectional transfer of DNA sequence information, occurs as a byproduct of recombinational repair of broken or damaged DNA molecules. Whereas excision repair processes replace damaged DNA by copying the complementary sequence from the undamaged strand of duplex DNA, recombinational mechanisms copy similar sequence, usually in another molecule, to replace the damaged sequence. In mitotic cells the other molecule is usually a sister chromatid, and the repair does not lead to genetic change. Less often a homologous chromosome or homologous sequence in an ectopic position is used. Conversion results from repair in two ways. First, if there was a double-strand gap at the site of a break, homologous sequence will be used as the template for synthesis to fill the gap, thus transferring sequence information in both strands. Second, recombinational repair uses complementary base pairing, and the heteroduplex molecule so formed is a source of conversion, both as heteroduplex and when donor (undamaged template) information is retained after correction of mismatched bases in heteroduplex. There are mechanisms that favour the use of sister molecules that must fail before ectopic homology can be used. Meiotic recombination events lead to the formation of crossovers required in meiosis for orderly segregation of pairs of homologous chromosomes. These events result from recombinational repair of programmed double-strand breaks, but in contrast with mitotic recombination, meiotic recombinational events occur predominantly between homologous chromosomes, so that transfer of sequence differences by conversion is very frequent. Transient recombination events that do not form crossovers form both between homologous chromosomes and between regions of ectopic homology, and leave their mark in the occurrence of frequent non-crossover conversion, including ectopic conversion.
Infrared coagulation versus rubber band ligation in early stage hemorrhoids
Gupta, P.J.;
Brazilian Journal of Medical and Biological Research , 2003, DOI: 10.1590/S0100-879X2003001000022
Abstract: the ideal therapy for early stages of hemorrhoids is always debated. some are more effective but are more painful, others are less painful but their efficacy is also lower. thus, comfort or efficacy is a major concern. in the present randomized study, a comparison is made between infrared coagulation and rubber band ligation in terms of effectiveness and discomfort. one hundred patients with second degree bleeding piles were randomized prospectively to either rubber band ligation (n = 54) or infrared coagulation (n = 46). parameters measured included postoperative discomfort and pain, time to return to work, relief in incidence of bleeding, and recurrence rate. the mean age was 38 years (range 19-68 years). the mean duration of disease was 17.5 months (range 12 to 34 months). the number of male patients was double that of females. postoperative pain during the first week was more intense in the band ligation group (2-5 vs 0-3 on a visual analogue scale). post-defecation pain was more intense with band ligation and so was rectal tenesmus (p = 0.0059). the patients in the infrared coagulation group resumed their duties earlier (2 vs 4 days, p = 0.03), but also had a higher recurrence or failure rate (p = 0.03). thus, we conclude that band ligation, although more effective in controlling symptoms and obliterating hemorrhoids, is associated with more pain and discomfort to the patient. as infrared coagulation can be conveniently repeated in case of recurrence, it could be considered to be a suitable alternative office procedure for the treatment of early stage hemorrhoids.
Análise comparativa do crescimento de biótipos de pic？o-preto (Bidens pilosa) resistente e suscetível aos herbicidas inibidores da ALS
Christoffoleti, P.J.;
Planta Daninha , 2001, DOI: 10.1590/S0100-83582001000100009
Abstract: the resistance of weed biotypes to acetolactate synthase (als) inhibitor herbicides is due to this enzyme's lack of sensitivity to als inhibitor herbicides, which inhibit its catalytic activity. als insensitivity results from a structural change in the aminoacid sequence, exactly in the site of action of these herbicides. eventually this modification in the enzyme may result in a reduced plant growth rate. such reduction was also observed in biotypes resistant to photosystem ii inhibitor herbicides. the possibility of a lower growth rate of the resistant plant may directly affect biotype competitiveness, its population dynamics and, as a consequence, resistance management strategies. the objective of this research was to compare the growth rates of both resistant and susceptible bidens pilosa biotypes to als inhibitor herbicides. the experiment was conducted in a greenhouse, using one plant per pot of 5 l capacity. four plants per biotype were harvested weekly, starting 14 days after planting, and the leaf area and dry biomass were measured. the richards function fitted to the data enabled the derivation of absolute growth rate, relative growth rate and net assimilation rate. the susceptible biotype had a higher biomass accumulation during the early stages, with both biotypes having the same size, afterwards. the higher net assimilation rate of the resistant biotype during the early stages of growth was balanced by its lower size during the first four weeks of growth. it was concluded that both biotypes have the same size, being very likely that resistant and susceptible bidens pilosa have the same competitiveness.
Partikuliere en Algemene Sinodes: 'n gereformeerde benadering/Particular and general synods
P.J Strauss
Acta Theologica , 2004,
Abstract: In this article the author investigates the character, composition and task of particular or regional synods and of general synods in reformed churches. Although the character and composition of these assemblies in the church can be defined fairly easily, the same can not be said of the distinction between the task of the former and the latter. The fact that both of them were called upon in the past to look after matters common to all congregations within its borders, created a vagueness in this regard. Which are those matters common to all congregations which should be attended to by particular synods and which by general synods? His solution is the application of two well-known principles of a reformed church polity: firstly, that major assemblies should not attend to matters which could be dealt with at minor assemblies, and, secondly, that a general synod should concentrate on those issues which are really common to all congregations in the specific denomination.
Die teologiese en morele regverdiging van Apartheid en ’n "status confessionis"
P.J Strauss
Acta Theologica , 2005,
Abstract: Beide die Wêreldbond van Gereformeerde Kerke (WBGK) en die — op daardie stadium — Gereformeerde Ekumeniese Sinode (GES) het eventueel verklaar dat die teologiese en morele regverdiging van apartheid ’n status confessionis daarstel. Veral die Afrikaanse gereformeerde kerke sou in dié verband onder skoot kom. Die vrae wat hierdie stuk vra is: Wanneer bereik die kerk die punt waar hy ’n status confessionis verklaar? Hoe het die WBGK en die GES hierdie saak hanteer en was daar verskille in hulle benadering wat na verskille in hulle karakter as ekumeniese liggame teruggevoer kan word? Die gevolgtrekking is dat die WBGK sekere anti-apartheidstemme in die jonger NG Kerke onkrities nagevolg het, terwyl die GES ’n meer selfstandige houding geopenbaar het. Die WBGK het ook nie apartheid gedefinieer nie, wat sake vir verdere gesprek met die NGK bemoeilik het. Beide vertoon egter tekens dat hulle ernstig probeer het om aan die vereistes vir ’n status confessionis te voldoen.
Commentary: Social Psychology and Developmental Psychology: Conversation or Collaboration?
Leman, P.J.
Papers on Social Representations , 2010,
Abstract:
Social relations, social influence and the development of knowledge
Leman, P.J.
Papers on Social Representations , 1998,
Abstract:
Kommunikasiekunde in Suid-Afrika: die begin, die hede en uitdagings vir die toekoms
P.J. Fourie
Koers : Bulletin for Christian Scholarship , 2009, DOI: 10.4102/koers.v74i1&2.122
Abstract: Communication science in South Africa: the beginnings, the present and challenges for the future This article is based on the Gert Pienaar Commemorative Lec-ture given by the author of this article on 27 August 2009 at the North-West University, Potchefstroom. The late Professor Gert Pienaar founded communication science (then Press Science) in South Africa, fifty years ago. Apart from acknowledging his contribution, the purpose of the lecture and of this article is to briefly outline the main research paradigms which have guided South African mass communication research the past fifty years, namely the positivist (or managerial) paradigm and the critical paradigm. It is argued that normative questions about the role and functions of the media in society underlie these paradigms. Against the background of new paradigms such as the postmodern and postcolonial paradigms (of which the basic tenets are also outlined) the applicability and relevance of old normative media theory in a new society and in a new media landscape (briefly described) are questioned and the Western prejudice of “old” normative theory is highlighted. With this in mind, four research areas for future South African mass com-munication research are emphasised, namely fundamental new media research, development communication research from an African perspective, communications policy research, and the indigenisation of mass communication theory.
Fritjof Capra’s holism and the structures of philosophical conceptualisation: The logosemantics of complexity
P.J. Visagie
Koers : Bulletin for Christian Scholarship , 1998, DOI: 10.4102/koers.v63i4.541
Abstract: This article explores a field of study that I call logosemantics: the theory of conceptual structures that determine philosophical expressions of ultimate insight. The kind of structures that logosemantics postulates are described with reference to the holistic philosophy of Capra. In particular the conceptualisation of holistic complexity in relation to reductionistic simplicity is thematised. In the course of this analysis the logosemantic place of complexity in the conceptual structure of philosophically foundational expressions is identified, with reference not only to Capra, but also to various philosophical "languages" in the history of Western thought, from Greek metaphysics to systems philosophy and post-structuralism. Attention is also given to some Eastern philosophies. After a purely descriptive analysis of logosemantic form, the possibility of logosemantic criticism is considered. The relation of simplicity and complexity is reviewed again, and an alternative interpretation to the one seemingly favoured by Capra is suggested.
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